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Healthcare

Image analysis

Medical Assistants

Generation of computer tomography scans from magnetic resonance images

Generation of computer tomography scans from magnetic resonance images

For:
Oncology hospitals, oncologists
Goal:
Improved Employee Efficiency
Problem addressed
Generation of a CT image from a given MRI image.
Scope of use case
Train a model that generates CT images from MRI scans. Synthetic CT images may be used for radiation dose calculation in radiation therapy.
Description
In this project, we investigate approaches to generating
synthetic computed tomography (CT) images from the real
magnetic resonance imaging (MRI) data. Generating
radiological scans has grown in popularity in recent years
due to its promise to enable single-modality radiotherapy
planning in clinical oncology, where the co-registration of
the radiological modalities is cumbersome. We rely on
generative adversarial network (GAN) models with cycle
consistency, which permit unpaired image-to-image
translation between the modalities. We also introduce the
perceptual loss function term and the coordinate
convolutional layer to further enhance the quality of
translated images. The Unsharp masking and the super-
resolution GAN (SRGAN) were considered to improve the
quality of synthetic images. The proposed architectures were
trained on unpaired MRI-CT data and then evaluated on a
paired brain dataset. The resulting CT scans were generated
with a mean absolute error (MAE), a peak signal-to-noise
ratio (PSNR) and structural similarity (SSIM) scores of 60,83
HU, 17,21 dB, and 0,8, respectively. DualGAN, with
perceptual loss function term and coordinated convolutional
layer, proved to perform best. The MRI-CT translation
approach holds the potential to eliminate the need for the
patients to undergo both examinations and to be clinically
accepted as a new tool for radiotherapy planning.
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Machine Learning
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